To monitor effectiveness of the treatment of leprosy, anti-PGL-1 ELISA test is
carrying out by the leprosy mobile team of Taegu Fatima hospital since 1989. A results
of the serial test in a old settlement village is summarized, and following are resulted.
1. Positivity(over 200) is declined from 36.6% to 18.8% respectively during over nine
years of MDT and so.
2. Up-grading(below 199→over 200) is revealed in both L & non-L group. (L:3
non-L:2)
3. Down-grading(down to lower scores) rate is similar in both group. (L:36.8%
non-L:33.3%)
4. Regardless of over nine years of triple MDT, no down-grading resulted in 29
cases(21.6%) and up-grading in 5 cases, which suggested resistant strains to dapsone,
rifampicin and clofazimin all together or separately.
5. Among 198 patients in this village, 99 cases(50.0%) are fit to national elimination
plan of completion of treatment and 51 cases(25.8%) are considered require close
observation of its trends for certain time, another words, 75.8% are qualified to the
Korean Screening regulation
6. Shifting of scores of anti-PGL-1 ELISA on serial examination suggests disease
activity as active Is supposed.
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